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Merck
CN

ABCG2

ATP-binding cassette, sub-family G (WHITE), member 2

别名:
ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1
物种:
Human ABCG2 (9429), Mouse Abcg2 (26357), Rat Abcg2 (312382), domestic guinea pig Abcg2 (100723442), domestic cat ABCG2 (101094017), chicken ABCG2 (423767), dog ABCG2 (478472), Horse ABCG2 (100034164), cow ABCG2 (536203), sheep ABCG2 (780508) ...展开
UniProtKB ID:
Q9UNQ0, A0A1W3, A8K1T5, O95374, Q53ZQ1, Q569L4, Q5YLG4, Q86V64
基因ID:
  • Human(9429) Summary: The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
  • Mouse(26357) ATP-binding cassette, sub-family G (WHITE), member 2
  • Rat(312382) ATP-binding cassette, subfamily G (WHITE), member 2
  • domestic guinea pig(100723442) ATP-binding cassette, sub-family G (WHITE), member 2
  • domestic cat(101094017) ATP-binding cassette, sub-family G (WHITE), member 2
  • chicken(423767) ATP-binding cassette, sub-family G (WHITE), member 2
  • dog(478472) ATP-binding cassette, sub-family G (WHITE), member 2
  • Horse(100034164) ATP-binding cassette, sub-family G (WHITE), member 2
  • cow(536203) ATP-binding cassette, sub-family G (WHITE), member 2
  • sheep(780508) ATP-binding cassette, sub-family G (WHITE), member 2
  • Domestic Rabbit(100008640) ATP-binding cassette, sub-family G (WHITE), member 2
  • Goat(100860857) ATP-binding cassette, sub-family G (WHITE), member 2

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Antibodies

Product Number
说明
物种反应性
应用
ZRB1217
抗-BCRP (ABCG2)抗体，克隆10K5，ZooMAb®兔单克隆抗体, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse
应用
immunocytochemistry
immunohistochemistry
western blot
MAB4145
Anti-BCRP Antibody, clone BXP-34, culture supernatant, clone BXP-34, Chemicon®,
物种反应性
human
应用
immunocytochemistry
immunohistochemistry
MAB4146
抗-BCRP抗体，克隆BXP-21, culture supernatant, clone BXP-21, Chemicon®,
物种反应性
human
应用
immunocytochemistry
immunohistochemistry
western blot
SAB1403023
Monoclonal Anti-ABCG2 antibody produced in mouse, clone 1G1, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
SAB5700094
Anti-ABCG2 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
western blot

Cell Lines

Product Number
说明
物种
SBVT17
SB-BCRP-HEK293, ,
物种
human
MTOX1002
BCRP Knockout Caco-2 Cells, one vial,
物种
human
MTOX1021
HepaRG™ Cells BCRP (-/-), one vial,
物种
human
MTOX1302
Canine MDR1 Knockout, Human BCRP/OATP2B1 double Knockin MDCKII Cells, ,
物种
human
MTOX1004
MDR1/BCRP Double Knockout Caco-2 Cells, one vial,
物种
human

Proteins

Product Number
说明
物种
SBAT06
BCRP human, membrane preparation for ATPase Assays, recombinant, expressed in baculovirus infected Sf9 cells,
物种
human

esiRNA

Product Number
说明
物种
EHU012921
MISSION® esiRNA, targeting human ABCG2,
物种
human
EMU090051
MISSION® esiRNA, targeting mouse Abcg2,
物种
mouse