ALOXE3
arachidonate lipoxygenase 3
别名:
ARCI3, E-LOX, eLOX3
物种:
Human ALOXE3 (59344), Mouse Aloxe3 (23801), Rat Aloxe3 (287424), domestic cat ALOXE3 (101101515), dog ALOXE3 (489487), Horse ALOXE3 (100062351), chicken ALOXE3 (425997), cow ALOXE3 (517001), sheep ALOXE3 (101121693), naked mole-rat Aloxe3 (101709560)
UniProtKB ID:
基因ID:
- Human(59344) Summary: This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
- Mouse(23801) arachidonate lipoxygenase 3
- Rat(287424) arachidonate lipoxygenase 3
- domestic cat(101101515) arachidonate lipoxygenase 3
- dog(489487) arachidonate lipoxygenase 3
- Horse(100062351) arachidonate lipoxygenase 3
- chicken(425997) arachidonate lipoxygenase 3
- cow(517001) arachidonate lipoxygenase 3
- sheep(101121693) arachidonate lipoxygenase 3
- naked mole-rat(101709560) arachidonate lipoxygenase 3
- domestic guinea pig(100731721) arachidonate lipoxygenase 3
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Antibodies
Product Number
说明
物种反应性
应用
Anti-ALOXE3 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-ALOXE3, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunohistochemistry
esiRNA
Product Number
说明
物种