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Merck
CN

ANAPC5

anaphase promoting complex subunit 5

别名:
APC5
物种:
UniProtKB ID:
基因ID:
  • Human(51433) Summary: This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008]
  • Mouse(59008) anaphase-promoting complex subunit 5
  • Rat(288671) anaphase-promoting complex subunit 5
  • sheep(101102840) anaphase promoting complex subunit 5
  • Domestic Rabbit(100350286) anaphase promoting complex subunit 5
  • domestic guinea pig(100726899) anaphase promoting complex subunit 5
  • naked mole-rat(101724399) anaphase promoting complex subunit 5
  • Zebrafish(322854) anaphase promoting complex subunit 5
  • chicken(416842) anaphase promoting complex subunit 5
  • dog(477471) anaphase promoting complex subunit 5
  • Horse(100058548) anaphase promoting complex subunit 5
  • cow(540537) anaphase promoting complex subunit 5

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Antibodies

Product Number
说明
物种反应性
应用
Anti-ANAPC5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-ANAPC5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Anti-APC5 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry

western blot

esiRNA

Product Number
说明
物种
MISSION® esiRNA, targeting mouse Anapc5,
物种
mouse
MISSION® esiRNA, targeting human ANAPC5,
物种
human