Merck
CN

BAX

BCL2-associated X protein

别名:
BCL2L4
物种:
UniProtKB ID:
基因ID:
  • Human(581) Summary: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12028) BCL2-associated X protein
  • Rat(24887) Bcl2-associated X protein
  • domestic cat(493837) BCL2-associated X protein
  • dog(403523) BCL2-associated X protein
  • cow(280730) BCL2-associated X protein
  • sheep(443059) BCL2-associated X protein
  • Goat(100846984) BCL2-associated X protein
  • naked mole-rat(101713575) BCL2-associated X protein
  • domestic guinea pig(100730890) BCL2-associated X protein

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Antibodies

货号
说明
物种反应性
应用
Anti-Bax Antibody, clone 6A7, clone 6A7, from mouse,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunoprecipitation (IP)

western blot
Anti-BAX antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-Bax (NT) Antibody, from rabbit,
物种反应性
bovine, canine, chimpanzee, feline, human, rhesus monkey
应用
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Bax Antibody, clone 1C7, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human
应用
immunocytochemistry
immunofluorescence

immunohistochemistry

western blot
抗 BAX 兔抗, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

western blot

Cell Lines

货号
说明
物种
SW48 Cells BAX -/-, ,
物种
human
DLD1 Cells BAX -/-, ,
物种
human
DLD1 Cells BAX/BAK (-/-,-/-), ,
物种
human
SW48 Cells BAX/BAK (-/-,-/-), ,
物种
human

Proteins

货号
说明
物种
BAX, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human BAX,
物种
human