BRWD1
bromodomain and WD repeat domain containing 1
Synonyms:
C21orf107, N143, WDR9
Species:
Human BRWD1 (54014), Mouse Brwd1 (93871), Rat Brwd1 (304061), Domestic Rabbit BRWD1 (100328651), naked mole-rat Brwd1 (101714700), domestic guinea pig Brwd1 (100713169), dog BRWD1 (487764), cow BRWD1 (540661), chicken BRWD1 (418521), sheep BRWD1 (101117901)
UniProtKB ID:
Gene ID:
- Human(54014) Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.[provided by RefSeq, Jun 2011]
- Mouse(93871) bromodomain and WD repeat domain containing 1
- Rat(304061) bromodomain and WD repeat domain containing 1
- Domestic Rabbit(100328651) bromodomain and WD repeat domain containing 1
- naked mole-rat(101714700) bromodomain and WD repeat domain containing 1
- domestic guinea pig(100713169) bromodomain and WD repeat domain containing 1
- dog(487764) bromodomain and WD repeat domain containing 1
- cow(540661) bromodomain and WD repeat domain containing 1
- chicken(418521) bromodomain and WD repeat domain containing 1
- sheep(101117901) bromodomain and WD repeat domain containing 1
- Zebrafish(798858) bromodomain and WD repeat domain containing 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-BRWD1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-BRWD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-BRWD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-BRWD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Proteins
Product Number
Description
Species