Merck
CN

CAMK2B

calcium/calmodulin-dependent protein kinase II beta

Synonyms:
CAM2, CAMK2, CAMKB
Species:
UniProtKB ID:
Gene ID:
  • Human(816) Summary: The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12323) calcium/calmodulin-dependent protein kinase II, beta
  • Rat(24245) calcium/calmodulin-dependent protein kinase II beta
  • cow(525416) calcium/calmodulin-dependent protein kinase II beta
  • Horse(100146368) calcium/calmodulin-dependent protein kinase II beta
  • domestic cat(101098615) calcium/calmodulin-dependent protein kinase II beta
  • chicken(374174) calcium/calmodulin-dependent protein kinase II beta
  • dog(608846) calcium/calmodulin-dependent protein kinase II beta
  • naked mole-rat(101718749) calcium/calmodulin-dependent protein kinase II beta
  • domestic guinea pig(100717077) calcium/calmodulin-dependent protein kinase II beta
  • sheep(101118870) calcium/calmodulin-dependent protein kinase II beta

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

Product Number
Description
Species
N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide hydrochloride, ,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-CaMK2-β/γ/δ (pThr287) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-CaMKII Antibody, clone 7L9F0, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Monoclonal Anti-CAMK2B antibody produced in mouse, clone S11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Monoclonal Anti-CAMK2B antibody produced in mouse, clone 6D6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Monoclonal Anti-CAMK2B antibody produced in mouse, clone S12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA

Proteins

Product Number
Description
Species
CAMK2β, active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
Calmodulin-dependent Protein Kinase II fragment 290-309, ≥97% (HPLC),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CAMK2B,
Species
human

Small Molecule - Substrate

Product Number
Description
Species
Autocamtide 2-related inhibitory peptide, ≥97% (HPLC), lyophilized powder,
Species
mouse, rat, human