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Merck
CN

CCR10

chemokine (C-C motif) receptor 10

别名:
GPR2
物种:
UniProtKB ID:
基因ID:
  • Human(2826) Summary: Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]
  • Mouse(12777) chemokine (C-C motif) receptor 10
  • Rat(363682) chemokine (C-C motif) receptor 10
  • domestic guinea pig(100720419) chemokine (C-C motif) receptor 10
  • Zebrafish(436948) chemokine (C-C motif) receptor 10
  • naked mole-rat(101714793) chemokine (C-C motif) receptor 10
  • cow(539108) chemokine (C-C motif) receptor 10
  • domestic cat(101092409) chemokine (C-C motif) receptor 10
  • dog(607528) chemokine (C-C motif) receptor 10
  • chicken(100858200) chemokine (C-C motif) receptor 10
  • Domestic Rabbit(100144330) chemokine (C-C motif) receptor 10
  • sheep(678671) chemokine (C-C motif) receptor 10

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Antibodies

Product Number
说明
物种反应性
应用
Anti-GPR2/CCR10 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunohistochemistry
Anti-CCR10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-CCR10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence

esiRNA

Product Number
说明
物种
MISSION® esiRNA, targeting mouse Ccr10,
物种
mouse