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CD86

CD86 molecule

Synonyms:
B7-2, B7.2, B70, CD28LG2, LAB72
Species:
UniProtKB ID:
Gene ID:
  • Human(942) Summary: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
  • Mouse(12524) CD86 antigen
  • Rat(56822) CD86 molecule
  • domestic guinea pig(101787434) CD86 molecule
  • naked mole-rat(101724342) CD86 molecule
  • chicken(427944) CD86 molecule
  • dog(403764) CD86 molecule
  • domestic cat(493704) CD86 molecule
  • cow(414345) CD86 molecule
  • Domestic Rabbit(100008999) CD86 molecule

Custom & Knockdown Gene Products

ELISA

Product Number
Description
Species
Rat CD86 / CD86 Antigen, Isoform CRA-c ELISA Kit, ,
Species
rat
Human CD86/B7-2 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-Cd86 antibody produced in rat, clone GL-1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
mouse
Application
flow cytometry
Monoclonal Anti-Cd86 low endotoxin antibody produced in rat, clone GL-1, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
mouse
Application
flow cytometry
Monoclonal Anti-CD86 antibody produced in mouse, clone BU63, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Monoclonal Anti-CD86-FITC antibody produced in mouse, clone BU63, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Anti-CD86 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
proximity ligation assay
western blot

Proteins

Product Number
Description
Species
CD86 human, recombinant, expressed in E. coli, 0.5 mg protein/mL,
Species
human
B7-2 (CD86), FC Fusion, Biotin Labeled, recombinant, expressed in HEK 293 cells,
Species
mouse

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CD86,
Species
human