Skip to Content
Merck
CN

DUS2

dihydrouridine synthase 2

Synonyms:
DUS2L, SMM1, URLC8
Species:
UniProtKB ID:
Gene ID:
  • Human(54920) Summary: This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]
  • Rat(291978) dihydrouridine synthase 2
  • Zebrafish(100003049) dihydrouridine synthase 2

Custom & Knockdown Gene Products

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human DUS2,
Species
human