HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
别名:
HERP, Mif1, SUP
物种:
Human HERPUD1 (9709), Mouse Herpud1 (64209), Rat Herpud1 (85430), sheep HERPUD1 (101121537), dog HERPUD1 (478116), domestic cat HERPUD1 (101082710), chicken HERPUD1 (415644), Zebrafish herpud1 (565499), naked mole-rat Herpud1 (101703450), domestic guinea pig Herpud1 (100725853)
UniProtKB ID:
基因ID:
- Human(9709) Summary: The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq, Jan 2013]
- Mouse(64209) homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
- Rat(85430) homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
- sheep(101121537) homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
- dog(478116) homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
- domestic cat(101082710) homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
- chicken(415644) homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
- Zebrafish(565499) homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
- naked mole-rat(101703450) homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
- domestic guinea pig(100725853) homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
- cow(613577) homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
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Antibodies
产品编号
说明
物种反应性
应用
Anti-HERPUD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Anti-HERPUD1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Monoclonal Anti-HERPUD1 antibody produced in mouse, clone 3E10, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
Anti-HERPUD1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot