IRS1
insulin receptor substrate 1
Synonyms:
HIRS-1
Species:
Human IRS1 (3667), Mouse Irs1 (16367), Rat Irs1 (25467), chicken IRS1 (429262), chicken IRS1 (429126), domestic guinea pig Irs1 (100716939), naked mole-rat Irs1 (101708189), sheep IRS1 (101102293), Domestic Rabbit IRS1 (100339981), domestic cat IRS1 (100271862) ...More
UniProtKB ID:
Gene ID:
- Human(3667) Summary: This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009]
- Mouse(16367) insulin receptor substrate 1
- Rat(25467) insulin receptor substrate 1
- chicken(429262) insulin receptor substrate 1
- chicken(429126) insulin receptor substrate 1
- domestic guinea pig(100716939) insulin receptor substrate 1
- naked mole-rat(101708189) insulin receptor substrate 1
- sheep(101102293) insulin receptor substrate 1
- Domestic Rabbit(100339981) insulin receptor substrate 1
- domestic cat(100271862) insulin receptor substrate 1
- domestic cat(101087257) insulin receptor substrate 1
- cow(538598) insulin receptor substrate 1
- dog(486148) insulin receptor substrate 1
- Zebrafish(559281) insulin receptor substrate 1
- chicken(101749888) insulin receptor substrate 1
- chicken(101666036) insulin receptor substrate 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-IRS-1 (pSer307) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-phospho-IRS1 (Tyr628) mouse/ (Tyr632) human Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
western blot
Anti-IRS1 Antibody, clone AW58, rabbit monoclonal, culture supernatant, clone AW58, Upstate®,
Species Reactivity
human, mouse, rat
Application
immunoprecipitation (IP)
western blot
western blot
Anti-phospho-IRS1 Antibody (Tyr941), from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
western blot
Anti-phospho-IRS1 (Tyr612) Antibody, clone 1N14, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse
Application
immunohistochemistry
inhibition assay
western blot
inhibition assay
western blot
Proteins
Product Number
Description
Species
IRS1 (600-1245), GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
IRS1 (1-355), GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
