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Merck
CN

MANEA

mannosidase, endo-alpha

别名:
ENDO, hEndo
物种:
UniProtKB ID:
基因ID:
  • Human(79694) Summary: N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005 [PubMed 15677381]
  • Mouse(242362) mannosidase, endo-alpha
  • Rat(140808) mannosidase, endo-alpha
  • domestic guinea pig(100718937) mannosidase, endo-alpha
  • dog(481925) mannosidase, endo-alpha
  • chicken(421807) mannosidase, endo-alpha
  • Zebrafish(447827) mannosidase, endo-alpha
  • sheep(101106778) mannosidase, endo-alpha
  • cow(512853) mannosidase, endo-alpha
  • Horse(100065922) mannosidase, endo-alpha
  • domestic cat(101101567) mannosidase, endo-alpha
  • naked mole-rat(101724745) mannosidase, endo-alpha

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Antibodies

Product Number
说明
物种反应性
应用
Anti-MANEA antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-MANEA antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-MANEA antibody produced in rabbit, affinity isolated antibody,
物种反应性
dog, human, mouse, rat
应用
western blot

esiRNA

Product Number
说明
物种
MISSION® esiRNA, targeting mouse Manea,
物种
mouse
MISSION® esiRNA, targeting human MANEA,
物种
human