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Merck
CN

MARCH2

membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase

别名:
MARCH-II, RNF172
物种:
UniProtKB ID:
基因ID:
  • Human(51257) Summary: MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]
  • Mouse(224703) membrane-associated ring finger (C3HC4) 2
  • Rat(362849) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
  • Zebrafish(555611) membrane-associated ring finger (C3HC4) 2
  • domestic guinea pig(100733733) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
  • domestic cat(101090087) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
  • cow(508949) membrane-associated ring finger (C3HC4) 2
  • dog(611624) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
  • naked mole-rat(101720054) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
  • sheep(101103806) membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
  • chicken(420062) membrane-associated ring finger (C3HC4) 2

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Antibodies

Product Number
说明
物种反应性
应用
Monoclonal Anti-MARCH2 antibody produced in mouse, clone 7F3, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot

esiRNA

Product Number
说明
物种
MISSION® esiRNA, targeting human MARCH2,
物种
human