PANK2
pantothenate kinase 2
Synonyms:
C20orf48, HARP, HSS, NBIA1, PKAN
Species:
Human PANK2 (80025), Mouse Pank2 (74450), Rat Pank2 (296167), cow PANK2 (535933), naked mole-rat Pank2 (101707167), domestic cat PANK2 (101092510), Zebrafish pank2 (570866), sheep PANK2 (100217410), dog PANK2 (477168), chicken PANK2 (422935) ...More
UniProtKB ID:
Gene ID:
- Human(80025) Summary: This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(74450) pantothenate kinase 2
- Rat(296167) pantothenate kinase 2
- cow(535933) pantothenate kinase 2
- naked mole-rat(101707167) pantothenate kinase 2
- domestic cat(101092510) pantothenate kinase 2
- Zebrafish(570866) pantothenate kinase 2
- sheep(100217410) pantothenate kinase 2
- dog(477168) pantothenate kinase 2
- chicken(422935) pantothenate kinase 2
- domestic guinea pig(100736048) pantothenate kinase 2
- Thale Cress(829351) pantothenate kinase 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PANK2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PANK2 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
western blot