PCDHA11
protocadherin alpha 11
Synonyms:
CNR7, CNRN7, CNRS7, CRNR7, PCDH-ALPHA11
Species:
Human PCDHA11 (56138), Mouse Pcdha11 (12942), Rat Pcdha11 (394223), domestic guinea pig Pcdha11 (100715544), naked mole-rat Pcdha11 (101729513), chicken PCDHA11 (497221), dog PCDHA11 (607280), cow PCDHA11 (787381), domestic cat PCDHA11 (101092986)
UniProtKB ID:
Gene ID:
- Human(56138) Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
- Mouse(12942) protocadherin alpha 11
- Rat(394223) protocadherin alpha 11
- domestic guinea pig(100715544) protocadherin alpha 11
- naked mole-rat(101729513) protocadherin alpha 11
- chicken(497221) protocadherin alpha 11
- dog(607280) protocadherin alpha 11
- cow(787381) protocadherin alpha 11
- domestic cat(101092986) protocadherin alpha 11
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PCDHA11 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence