CN
PRNP
prion protein
Synonyms:
ASCR, AltPrP, CD230, CJD, GSS, KURU, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, p27-30
Species:
Human PRNP (5621), Mouse Prnp (19122), Rat Prnp (24686), domestic cat PRNP (493886), chicken PRNP (396452), Horse PRNP (100065904), naked mole-rat Prnp (101710391), cow PRNP (281427), domestic guinea pig Prnp (100714701), sheep PRNP (493887) ...More
UniProtKB ID:
Gene ID:
- Human(5621) Summary: The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
- Mouse(19122) prion protein
- Rat(24686) prion protein
- domestic cat(493886) prion protein
- chicken(396452) prion protein
- Horse(100065904) prion protein
- naked mole-rat(101710391) prion protein
- cow(281427) prion protein
- domestic guinea pig(100714701) prion protein
- sheep(493887) prion protein
- Domestic Rabbit(100345744) prion protein
- dog(485783) prion protein
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Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Prion Protein Antibody, NT, a.a. 78-97, serum, Chemicon®,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Prion Protein Antibody, clone POM2, clone POM2, from mouse,
Species Reactivity
human, mouse
Application
ELISA
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-Prion Protein Antibody, clone 12D6.1, clone 12D6.1, from mouse,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-Prion Protein Antibody, Chemicon®, from mouse,
Species Reactivity
bovine, elk, mouse, mule deer, sheep
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-CD230 antibody produced in mouse, clone EM-20,
Species Reactivity
human
Application
western blot
Proteins
esiRNA
Product Number
Description
Species