CN
PTGIS
prostaglandin I2 (prostacyclin) synthase
别名:
CYP8, CYP8A1, PGIS, PTGI
物种:
Human PTGIS (5740), Mouse Ptgis (19223), Rat Ptgis (25527), dog PTGIS (485919), Goat PTGIS (100860894), cow PTGIS (282021), domestic guinea pig Ptgis (100734621), Zebrafish ptgis (559148), sheep PTGIS (101116418), Horse PTGIS (100071412) ...展开
UniProtKB ID:
基因ID:
- Human(5740) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008]
- Mouse(19223) prostaglandin I2 (prostacyclin) synthase
- Rat(25527) prostaglandin I2 (prostacyclin) synthase
- dog(485919) prostaglandin I2 (prostacyclin) synthase
- Goat(100860894) prostaglandin I2 (prostacyclin) synthase
- cow(282021) prostaglandin I2 (prostacyclin) synthase
- domestic guinea pig(100734621) prostaglandin I2 (prostacyclin) synthase
- Zebrafish(559148) prostaglandin I2 (prostacyclin) synthase
- sheep(101116418) prostaglandin I2 (prostacyclin) synthase
- Horse(100071412) prostaglandin I2 (prostacyclin) synthase
- naked mole-rat(101700601) prostaglandin I2 (prostacyclin) synthase
- domestic cat(101082050) prostaglandin I2 (prostacyclin) synthase
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Antibodies
货号
说明
物种反应性
应用
Anti-PTGIS antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Anti-PTGIS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-PTGIS antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, human, mouse, rat
应用
western blot
Monoclonal Anti-PTGIS, (C-terminal) antibody produced in mouse, clone 3B11, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
Anti-PTGIS antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Small Molecule - Ligand
货号
说明
物种