SIAH1
siah E3 ubiquitin protein ligase 1
Synonyms:
SIAH1A
Species:
Human SIAH1 (6477), dog SIAH1 (487293), Zebrafish siah1 (80955), sheep SIAH1 (101111116), domestic cat SIAH1 (101090311), domestic guinea pig Siah1 (100722988), chicken SIAH1 (374076), naked mole-rat Siah1 (101702094), cow SIAH1 (534655)
UniProtKB ID:
Gene ID:
- Human(6477) Summary: This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]
- dog(487293) siah E3 ubiquitin protein ligase 1
- Zebrafish(80955) seven in absentia homolog 1 (Drosophila)
- sheep(101111116) siah E3 ubiquitin protein ligase 1
- domestic cat(101090311) siah E3 ubiquitin protein ligase 1
- domestic guinea pig(100722988) siah E3 ubiquitin protein ligase 1
- chicken(374076) seven in absentia homolog 1 (Drosophila)
- naked mole-rat(101702094) siah E3 ubiquitin protein ligase 1
- cow(534655) seven in absentia homolog 1 (Drosophila)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SIAH1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-SIAH1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Anti-SIAH1 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-SIAH1 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-SIAH1, (N-terminal) antibody produced in mouse, clone 2C5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
esiRNA
Product Number
Description
Species