TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
Synonyms:
MAP3K7IP3, NAP1
Species:
Human TAB3 (257397), Mouse Tab3 (66724), Rat Tab3 (317546), dog TAB3 (491807), domestic guinea pig Tab3 (100726447), Horse TAB3 (100051087), domestic cat TAB3 (101101545), sheep TAB3 (101119184), chicken TAB3 (418588), naked mole-rat Tab3 (101718111) ...More
UniProtKB ID:
Gene ID:
- Human(257397) Summary: The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
- Mouse(66724) TGF-beta activated kinase 1/MAP3K7 binding protein 3
- Rat(317546) TGF-beta activated kinase 1/MAP3K7 binding protein 3
- dog(491807) TGF-beta activated kinase 1/MAP3K7 binding protein 3
- domestic guinea pig(100726447) TGF-beta activated kinase 1/MAP3K7 binding protein 3
- Horse(100051087) TGF-beta activated kinase 1/MAP3K7 binding protein 3
- domestic cat(101101545) TGF-beta activated kinase 1/MAP3K7 binding protein 3
- sheep(101119184) TGF-beta activated kinase 1/MAP3K7 binding protein 3
- chicken(418588) TGF-beta activated kinase 1/MAP3K7 binding protein 3
- naked mole-rat(101718111) TGF-beta activated kinase 1/MAP3K7 binding protein 3
- Zebrafish(566547) TGF-beta activated kinase 1/MAP3K7 binding protein 3
- cow(788288) TGF-beta activated kinase 1/MAP3K7 binding protein 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-TAB3 Antibody, clone 3Y6T7, Rabbit Monoclonal, ,
Species Reactivity
mouse
Application
western blot
Anti-TAB3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
esiRNA
Product Number
Description
Species