TLX1
T-cell leukemia homeobox 1
Synonyms:
HOX11, TCL3
Species:
Human TLX1 (3195), Mouse Tlx1 (21908), Rat Tlx1 (499361), cow TLX1 (505304), Zebrafish tlx1 (266964), dog TLX1 (608311), sheep TLX1 (101112937), domestic cat TLX1 (101096848), chicken TLX1 (395868), domestic guinea pig Tlx1 (100730661)
UniProtKB ID:
Gene ID:
- Human(3195) Summary: This gene encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]
- Mouse(21908) T cell leukemia, homeobox 1
- Rat(499361) T-cell leukemia, homeobox 1
- cow(505304) T-cell leukemia homeobox 1
- Zebrafish(266964) T-cell leukemia, homeobox 1
- dog(608311) T-cell leukemia homeobox 1
- sheep(101112937) T-cell leukemia homeobox 1
- domestic cat(101096848) T-cell leukemia homeobox 1
- chicken(395868) T-cell leukemia homeobox 1
- domestic guinea pig(100730661) T-cell leukemia homeobox 1
- naked mole-rat(101725642) T-cell leukemia homeobox 1
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