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Merck
CN

UGCG

UDP-glucose ceramide glucosyltransferase

Synonyms:
GCS, GLCT1
Species:
UniProtKB ID:
Gene ID:
  • Human(7357) Summary: Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular processes. UDP-glucose ceramide glucosyltransferase catalyzes the first glycosylation step in glycosphingolipid biosynthesis. The product, glucosylceramide, is the core structure of more than 300 GSLs. UGCG is widely expressed and transcription is upregulated during keratinocyte differentiation. [provided by RefSeq, Oct 2009]
  • Mouse(22234) UDP-glucose ceramide glucosyltransferase
  • Rat(83626) UDP-glucose ceramide glucosyltransferase
  • chicken(427335) UDP-glucose ceramide glucosyltransferase
  • Zebrafish(553944) UDP-glucose ceramide glucosyltransferase
  • domestic cat(101101006) UDP-glucose ceramide glucosyltransferase
  • dog(481666) UDP-glucose ceramide glucosyltransferase
  • cow(514357) UDP-glucose ceramide glucosyltransferase
  • Horse(100057611) UDP-glucose ceramide glucosyltransferase
  • domestic guinea pig(100730880) UDP-glucose ceramide glucosyltransferase
  • sheep(101111687) UDP-glucose ceramide glucosyltransferase

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-UGCG antibody produced in mouse, clone 1E5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-UGCG antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-UGCG antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
N-Butyldeoxynojirimycin, film (dried in situ),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human UGCG,
Species
human
MISSION® esiRNA, targeting mouse Ugcg,
Species
mouse