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VAV3

vav 3 guanine nucleotide exchange factor

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(10451) Summary: This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(57257) vav 3 oncogene
  • Rat(295378) vav 3 guanine nucleotide exchange factor
  • chicken(373939) vav 3 guanine nucleotide exchange factor
  • domestic cat(101087417) vav 3 guanine nucleotide exchange factor
  • Domestic Rabbit(100341627) vav 3 guanine nucleotide exchange factor
  • dog(479921) vav 3 guanine nucleotide exchange factor
  • domestic guinea pig(100714719) vav 3 guanine nucleotide exchange factor
  • Horse(100057737) vav 3 guanine nucleotide exchange factor
  • cow(521961) vav 3 guanine nucleotide exchange factor
  • naked mole-rat(101716743) vav 3 guanine nucleotide exchange factor
  • sheep(101120709) vav 3 guanine nucleotide exchange factor

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-VAV3 Antibody, clone 9A10D8, Rabbit Monoclonal, ,
Species Reactivity
mouse
Application
immunohistochemistry
western blot
Anti-Vav3 Antibody, human, Upstate®, from rabbit,
Species Reactivity
human
Application
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-VAV3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
flow cytometry

immunofluorescence

immunohistochemistry
Anti Vav1/2/3 Antibody, clone 24GB2645, Rabbit Monoclonal, clone 24GB2645, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human
Application
immunofluorescence
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human VAV3,
Species
human