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About This Item
Empirical Formula (Hill Notation):
C27H48O
CAS Number:
Molecular Weight:
388.67
NACRES:
NA.25
UNSPSC Code:
12352211
InChI
1S/C27H48O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h18-25,28H,6-17H2,1-5H3
InChI key
QYIXCDOBOSTCEI-UHFFFAOYSA-N
SMILES string
[H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)C3CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCCC(C)C
description
5α-cholestan-3β-ol
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 5 mg (700064P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
General description
Cholestanol is a 5α-dihydro derivative of cholesterol. It acts as a marker for cholesterol absorption. Cholestanol is a steroid with 27 carbon atoms.
Packaging
5 mL Amber Glass Screw Cap Vial (700064P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Cholestanol metabolism in patients with cerebrotendinous xanthomatosis: absorption, turnover, and tissue deposition
Bhattacharyya AK, et al.
Journal of Lipid Research, 48(1), 185-192 (2007)
Addictive Substances and Neurological Disease: Alcohol, Tobacco, Caffeine, and Drugs of Abuse in Everyday Lifestyles, 184(2), 247-254 (2017)
Michel R Hoenig et al.
Atherosclerosis, 184(2), 247-254 (2005-10-12)
Statins have been the mainstay of lipid-lowering therapy since their introduction. However, as lower LDL cholesterol targets are sought, adjunct therapies are becoming increasingly important. Few patients reach new targets with statin monotherapy. We propose that the cholestanol:cholesterol ratio can
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