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NACRES:
NA.84
UNSPSC Code:
12161503
Species reactivity:
human
Technique(s):
single molecule counting: suitable
Usage:
kit sufficient for 96 wells
Compatibility:
for use with for use with FemtoQuest™ and SMCxPRO® instruments (validated)
产品名称
SMC® 淀粉样β42高灵敏度试剂盒,
Quality Segment
description
Used for ultrasensitive quantification of Amyloid Beta 1-42 (Aβ42) in human, rat or mouse plasma or cerebrospinal fluid (CSF)
product line
SMC®
usage
kit sufficient for 96 wells
species reactivity
human
technique(s)
single molecule counting: suitable
input
serum
plasma
cerebrospinal fluid (CSF)
compatibility
for use with for use with FemtoQuest™ and SMCxPRO® instruments (validated)
shipped in
wet ice
storage temp.
2-8°C
General description
SMC® 淀粉样蛋白 β 1-42 高灵敏度免疫检测试剂盒包含进行测定所需的所有试剂。该测定采用标准免疫测定工作流程,配置标准板形式。
测定方案与现有的夹心 ELISA 方法相似,但有两个主要区别:
1)洗脱缓冲液破坏三明治,分离标记的检测抗体用于进行定量。
2)Erenna 和 SMCxPRO® 免疫测定系统使用单分子计数(SMC®)技术检测分析物。
测定方案与现有的夹心 ELISA 方法相似,但有两个主要区别:
1)洗脱缓冲液破坏三明治,分离标记的检测抗体用于进行定量。
2)Erenna 和 SMCxPRO® 免疫测定系统使用单分子计数(SMC®)技术检测分析物。
Application
Neuroscience/Neurological Disorders/Signaling
Features and Benefits
- High Sensitivity Detection: Precisely quantifies Amyloid Beta 1-42 at femtogram/mL levels in plasma or CSF.
- Improved Dynamic Range: Enhanced signal-to-noise ratio with reduced background interference for reliable assay performance.
- User-Friendly Workflow: Utilizes a familiar sandwich immunoassay format while ensuring high sensitivity for Aβ1-42 detection.
- Automation-Ready: Compatible with automated liquid handling systems, reducing manual steps and increasing lab efficiency.
Packaging
96 well assay
Analysis Note
- Sensitivity: LLOQ 980 fg/mL* (SMCxPRO® Instrument)
- Standard Curve Range: 244-250,000 fg/mL
- Intra-assay CV: <15%
- Inter-assay CV: <20%
- Linearity: CSF: 100%
- Recovery: Plasma: 94% CSF: 92%
*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.
Other Notes
Although Amyloid Beta 42 was detectable in mouse and rat samples, the assay has not been verified for these species.
Legal Information
FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany
SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
signalword
Danger
target_organs
Respiratory Tract
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - ED ENV 1 - Eye Irrit. 2 - Repr. 1B - STOT RE 2 Inhalation

