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Merck
CN

03-0153-00

SMC®胰高血糖素高灵敏度试剂盒

Used for ultrasensitive quantification of Glucagon in human, rat or mouse plasma

别名:

Glucagon Single Molecule Counting Kit, Glucagon ultra-sensitive immunoassay, Pro-glucagon immunoassay kit

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NACRES:
NA.84
UNSPSC Code:
12161503
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产品名称

SMC®胰高血糖素高灵敏度试剂盒, Used for ultrasensitive quantification of Glucagon in human, rat or mouse plasma

product line

SMC®

usage

 kit sufficient for 96 wells

quality

200

species reactivity

human, mouse, rat

manufacturer/tradename

SMC®

technique(s)

single molecule counting: suitable

input

plasma (K2 EDTA)

UniProt accession no.

compatibility

for use with FemtoQuest and SMCxPRO® instruments

shipped in

wet ice

storage temp.

2-8°C

Biochem/physiol Actions

胰高血糖素(人)是 100% 可检测的。
催产调节蛋白(人)可检测到 <0.5%。
GLP-1(人)检测不到。
GLP-2(人)检测不到。
GIP(人)检测不到。

Disclaimer

我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

Legal Information

SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany

Analysis Note

Metabolism
Endocrinology
  • Sensitivity: LLOQ 781 fg/mL* (SMCxPRO® Instrument)
  • Standard Curve Range: 200-200,000 fg/mL
  • Intra-assay CV: <15%
  • Inter-assay CV: <20%
  • Linearity: Plasma: 86%
  • Recovery: Plasma: 86%
  • *Indicative LLOQ created from average of 14 independent in house runs,where >80% met same value defined with CV & Recovery +/- 20%. Refer toCoA for lot specific performance.

Application

Metabolism

Features and Benefits

  • Ultra-Sensitive Detection — Quantifies glucagon down to 0.20 pg/mL
  • Wide Dynamic Range — Covers 0.20–200 pg/mL
  • SMC® Technology — Enables single molecule resolution for precise quantification
  • Species Compatibility — Validated for human, mouse, and rat plasma
  • Detect Glucagon at Femto-Level Sensitivity — Ideal for metabolic and endocrine research
  • Reliable Across Species — Supports translational studies from animal models to human samples
  • Accurate Results with Minimal Interference — Trusted data in complex biological fluids

Packaging

96 well assay

General description

Glucagon is a peptide hormone secreted by pancreatic alphacells that plays a vital role in maintaining glucose homeostasis. It acts as acounter-regulatory hormone to insulin by stimulating glycogenolysis andgluconeogenesis in the liver, thereby increasing blood glucose levels duringfasting or hypoglycemia. In addition to its role in glucose metabolism,glucagon also influences lipid metabolism and energy balance, making it a keybiomarker in metabolic and endocrine research.

Altered glucagon levels are associated with metabolicdisorders such as type 2 diabetes, obesity, and insulin resistance. Accuratemeasurement of glucagon is essential for understanding pancreatic function,evaluating therapeutic interventions, and studying the hormonal regulation ofenergy metabolism.

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B - STOT RE 2 Inhalation

target_organs

Respiratory Tract

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

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Explore ultrasensitive immunoassay technology with SMC® technology, including its biomarker detection platform, advantages of high sensitivity assays, and more.

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