产品名称
SMC® 人白细胞介素6(IL-6)高灵敏度免疫测定试剂盒, Used for ultrasensitive quantification of Human IL-6 in human serum and plasma
product line
SMC®
usage
kit sufficient for 96 wells
species reactivity
human
manufacturer/tradename
SMC®
technique(s)
single molecule counting: suitable
input
plasma (K2 EDTA)
serum
UniProt accession no.
compatibility
for use with FemtoQuest™ and SMCxPRO® instruments
shipped in
wet ice
Legal Information
Analysis Note
- Sensitivity: LLOQ 88 fg/mL* (SMCxPRO® Instrument
- Standard Curve Range: 10-50,000 fg/mL
- Intra-assay CV: <15%
- Inter-assay CV: <20%
- Linearity: Serum: 115% Plasma: 112%
- Recovery: Serum: 112% Plasma: 100%
*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.
Application
Biochem/physiol Actions
Disclaimer
Features and Benefits
- Ultra-Low Detection Limits: Enables femtogram-level detection of IL-6, far surpassing traditional ELISA sensitivity.
- Expanded Dynamic Range: Reduces background noise, improving assay performance.
- Targeted Research Applications: Ideal for sudies in inflammation, autoimmune diseases, and biomarker discovery.
- Streamlined Lab Operations: Automation-ready reagents help optimize workflow and reduce manual handling.
- Robust Performance: Supports preclinical and translational research with dependable results, enhancing quality of scientific investigations.
- Advanced Technology: Powered by SMC®Technology for enhanced sensitivity.
General description
IL-6 is important in the study of diseases such as diabetes, lupus, multiple myeloma, rheumatoid arthritis and some cancers such as prostate and pancreatic cancer. Conversely, deficiency of IL-6 can have an effect on immune activation and IgA antibodies while overexpression of IL-6 can result in an immunological imbalance leading to an autoimmune pathology.
Packaging
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
法规信息
相关内容
通过适合的免疫检测产品,探索神经免疫和神经炎症细胞因子及神经退行性疾病生物标志物。
Read an automated protocol for SMC® immunoassays on the AAW™ automated assay workstation and compare manual vs automated runs.
Reduce sources of error and variability in sensitive methods to quantify biomarkers by automating the SMC® immunoassay workflow with the Hamilton Microlab® STARlet liquid handling workstation.
Use the power of high sensitivity immunology assays with SMC® technology to precisely characterize low-abundant cytokines like those from Th1/Th2 and Th17 cells.
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