species reactivity
human
manufacturer/tradename
Milliplex®
assay range
accuracy: 92-107%, standard curve range: 0.01-50 ng/mL
(Extracellular matrix protein 1), standard curve range: 0.48-2,000 ng/mL
(All other biomarkers)
technique(s)
multiplexing: suitable
detection method
fluorometric (Luminex xMAP)
shipped in
wet ice
Quality Level
General description
Circulating cancer biomarkers give insight beyond intracellular oncogenesis and into how the body responds to the presence of a tumor, the dysregulation of homeostasis, and the relationship between a tumor and its environment. Multianalyte panels have become essential tools that enable researchers to measure cancer biomarkers simultaneously, teasing out these relationships and applying them to understand tumor biology.
MILLIPLEX® Circulating Cancer Biomarker Panel 2 is a 4-plex kit that can be used for the simultaneous quantification of any or all of the following analytes in serum, plasma, tissue/cell lysate and culture supernatant samples: Extracellular matrix Protein 1 (ECM1), Antithrombin III, Vitamin D binding protein, and Complement Factor H (CFH). This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.
The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.
Panel Type: Circulating Cancer
MILLIPLEX® Circulating Cancer Biomarker Panel 2 is a 4-plex kit that can be used for the simultaneous quantification of any or all of the following analytes in serum, plasma, tissue/cell lysate and culture supernatant samples: Extracellular matrix Protein 1 (ECM1), Antithrombin III, Vitamin D binding protein, and Complement Factor H (CFH). This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.
The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.
Panel Type: Circulating Cancer
Application
- Analytes: Antithrombin III, Complement Factor H (CFH), Extracellular matrix Protein 1 (ECM1), Vitamin D binding protein
- Recommended Sample Type: Human serum, plasma or tissue/cell culture supernatants or lysates
- Note: Serum has a thrombin/antithrombin III complex bound to vitronectin. To accurately quantify antithrombin III concentrations we recommend using plasma samples because they lack the vitronectin/thrombin/antithrombin complex.
- Recommended Sample Dilution: 25 μL of a 1:10,000 dilution of plasma or serum, or 25 μL of tissue/cell culture sample diluted in an appropriate control medium (dilution factors may vary)
- Assay Run Time: Overnight (16-18 hours) at 2-8°C
- Research Category: Cancer
Features and Benefits
Design your multiplex kit by choosing available analytes within this panel.
Other Notes
Human Circulating Cancer Biomarker Panel 2 Standard (HCC-8058-2)
Human Circulating Cancer Biomarker Panel 2 Quality Controls 1 and 2 (HCC-6058-2)
Set of one 96-Well Plate with 2 Sealers
Bead Diluent (LBD-4)
Assay Buffer (L-AB)
Note: Contains 0.08% Sodium Azide
10X Wash Buffer (L-WB)
Note: Contains 0.05% Proclin
Human Circulating Cancer Biomarker Panel 2 Detection Antibodies (HCC-1058)
Streptavidin-Phycoerythrin (L-SAPE 6)
Human Circulating Cancer Biomarker Panel 2 Quality Controls 1 and 2 (HCC-6058-2)
Set of one 96-Well Plate with 2 Sealers
Bead Diluent (LBD-4)
Assay Buffer (L-AB)
Note: Contains 0.08% Sodium Azide
10X Wash Buffer (L-WB)
Note: Contains 0.05% Proclin
Human Circulating Cancer Biomarker Panel 2 Detection Antibodies (HCC-1058)
Streptavidin-Phycoerythrin (L-SAPE 6)
Sensitivity: Refer to kit protocol for sensitivities of individual biomarkers.
Legal Information
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
target_organs
Respiratory Tract
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
法规信息
新产品
此项目有
Ginette Tardif et al.
Arthritis research & therapy, 24(1), 120-120 (2022-05-24)
Osteoarthritis (OA) is a slowly developing and debilitating disease, and there are no validated specific biomarkers for its early detection. To improve therapeutic approaches, identification of specific molecules/biomarkers enabling early determination of this disease is needed. This study aimed at
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持


