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Merck
CN

14366C

EX-CELL® Advanced CHO Fed-batch培养基

liquid

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关于此项目

NACRES:
NA.75
UNSPSC Code:
41161501
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产品名称

EX-CELL® Advanced CHO Fed-batch培养基, liquid

sterility

sterile-filtered

product line

EX-CELL®

form

liquid

technique(s)

cell culture | mammalian: suitable (suspension)

components

L-glutamine: no

shipped in

ambient

storage temp.

2-8°C

Quality Level

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General description

EX-CELL® AdvancedCHO Fed-batch培养基化学成分明确且不含有动物来源成分 。来自SAFC的最新平台 经过特别开发设计,用于维持 各种中国仓鼠卵巢(CHO)细胞的生长和生产,同时可灵活 调节蛋白质的质量属性。这种 实时分批补料平台采用多变量分析策略开发, 以确定配方成分影响关键过程和产品属性 (如滴度、 褶皱膨胀(fold expansion)、受体表达、 和T糖基化)的相关性。该平台 不含次黄嘌呤和胸苷、L-谷氨酰胺、酚红或 2-巯基乙醇(2-ME)。 该培养基设计用于用于分批补料平台,并与 EX-CELL® Advanced CHO Feed 1 (24367C - 含葡萄糖或24368C -不含葡萄糖)一起使用。

Legal Information

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

动植物来源培养基
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Weiyi Liu et al.
Biotechnology progress, 37(1), e3061-e3061 (2020-08-05)
Antibody-dependent cellular cytotoxicity (ADCC) is the primary mechanism of actions for several marketed therapeutic antibodies (mAbs) and for many more in clinical trials. The ADCC efficacy is highly dependent on the ability of therapeutic mAbs to recruit effector cells such

商品

In this study, nine commercially available, chemically defined media and feed combinations from different vendors were assessed for producing monoclonal antibody in Chinese hamster ovary (CHO) cells.

Discover how low-impurity iron sources improve reliability and performance in recombinant protein production with EX-CELL® Advanced medium.

This case study walks through optimizing feed and media for upstream bioprocessing and how it translates to large-scale bioreactors.

Cellvento® and EX-CELL® CHO cell culture media and feeds, optimized for monoclonal antibody & recombinant protein production in fed-batch & perfusion

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