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线性分子式:
NH2(CH2)3NH(CH2)4NH2 · 3HCl
化学文摘社编号:
分子量:
254.63
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
206-379-0
MDL number:
Beilstein/REAXYS Number:
3552356
产品名称
亚精胺 三盐酸盐, ≥99.0% (AT)
InChI key
LCNBIHVSOPXFMR-UHFFFAOYSA-N
InChI
1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H
SMILES string
Cl[H].Cl[H].Cl[H].NCCCCNCCCN
biological source
microbial
synthetic
assay
≥99.0% (AT)
form
powder
mp
~250 °C (dec.)
257-259 °C (lit.)
solubility
H2O: 0.1 g/mL, clear, colorless
storage temp.
room temp
Quality Level
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Application
三盐酸亚精胺可作为标准品通过HPLC用于检测生物胺。
Biochem/physiol Actions
亚精胺可调节多种细胞活动,如细胞发育和分化、DNA的稳定性和凋亡。
抑制神经元型一氧化氮合酶(nNOS)。结合并沉淀 DNA;刺激T4多核苷酸激酶活性。
抑制神经元型一氧化氮合酶(nNOS)。结合并沉淀DNA;可用于纯化DNA结合蛋白。刺激T4多核苷酸激酶活性。
Disclaimer
如果需要无菌溶液,则应采用无菌过滤而非高压灭菌。时间一长,亚精胺将发生脱氨基作用;溶液应采用冷冻保存。通常需要配制新溶液。
General description
亚精胺是一种多胺和三价有机阳离子。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Restriction Endonucleases and Modification Methylases
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Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, 231-247 (2016)
Quality Changes and Shelf-Life of Cultured and Wild Hot-Smoked Mediterranean Horse Mackerel (Trachurus mediterraneus, Steindachner, 1868) at Frozen Storage (-20 pm2 C)
Koral S, et al.
Turkish Journal of Fisheries and Aquatic Sciences, 15(3), 495-504 (2015)
Maegan J Watson et al.
Current protocols, 2(1), e344-e344 (2022-01-19)
The control of mRNA stability is fundamental to gene regulation, and a deeper understanding of this post-transcriptional regulatory step can provide key insights into gene function. Measuring mRNA half-lives directly, however, is challenging. The most common strategies for evaluating mRNA
Oliver Hendy et al.
Molecular cell, 82(19), 3598-3612 (2022-09-17)
Gene transcription is a highly regulated process in all animals. In Drosophila, two major transcriptional programs, housekeeping and developmental, have promoters with distinct regulatory compatibilities and nucleosome organization. However, it remains unclear how the differences in chromatin structure relate to
商品
Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.
一氧化氮 (NO) 是神经元、内皮细胞和免疫系统中的信号转运分子。
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