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Merck
CN

85580

亚精胺 三盐酸盐

From microbial,synthetic, ≥99.0% (AT), nNos inhibitor, powder

别名:

N-(3-氨基丙基)-1,4-丁二胺 三盐酸盐

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关于此项目

线性分子式:
NH2(CH2)3NH(CH2)4NH2 · 3HCl
化学文摘社编号:
分子量:
254.63
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
206-379-0
MDL number:
Beilstein/REAXYS Number:
3552356
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产品名称

亚精胺 三盐酸盐, ≥99.0% (AT)

InChI key

LCNBIHVSOPXFMR-UHFFFAOYSA-N

InChI

1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H

SMILES string

Cl[H].Cl[H].Cl[H].NCCCCNCCCN

biological source

microbial
synthetic

assay

≥99.0% (AT)

form

powder

mp

~250 °C (dec.)
257-259 °C (lit.)

solubility

H2O: 0.1 g/mL, clear, colorless

storage temp.

room temp

Quality Level

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Application

三盐酸亚精胺可作为标准品通过HPLC用于检测生物胺。

Biochem/physiol Actions

亚精胺可调节多种细胞活动,如细胞发育和分化、DNA的稳定性和凋亡。
抑制神经元型一氧化氮合酶(nNOS)。结合并沉淀 DNA;刺激T4多核苷酸激酶活性。
抑制神经元型一氧化氮合酶(nNOS)。结合并沉淀DNA;可用于纯化DNA结合蛋白。刺激T4多核苷酸激酶活性。

Disclaimer

如果需要无菌溶液,则应采用无菌过滤而非高压灭菌。时间一长,亚精胺将发生脱氨基作用;溶液应采用冷冻保存。通常需要配制新溶液。

General description

亚精胺是一种多胺和三价有机阳离子。

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Koral S, et al.
Turkish Journal of Fisheries and Aquatic Sciences, 15(3), 495-504 (2015)
Maegan J Watson et al.
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