Merck
CN
所有图片(5)

文件

安全信息

HPA058448

Sigma-Aldrich

Anti-TNNT1 antibody produced in rabbit

enhanced validation

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

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别名:
Anti-ANM, Anti-FLJ98147, Anti-MGC104241, Anti-NEM5, Anti-STNT, Anti-TNT, Anti-TNTS
人类蛋白质图谱编号:

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

产品线

Prestige Antibodies® Powered by Atlas Antibodies

形式

buffered aqueous glycerol solution

种属反应性

human

增强验证

orthogonal RNAseq
Learn more about Antibody Enhanced Validation

技术

immunohistochemistry: 1:500- 1:1000

免疫原序列

EEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGE

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... TNNT1(7138)

一般描述

Troponin T1 (TNNT1) is located on human chromosome 19q13.4. The encoded protein is composed of 261 amino acids and is expressed specifically in slow skeletal muscle.

免疫原

troponin T type 1 (skeletal, slow)

应用

Anti-TNNT1 antibody has been used in immunohistochemical staining.

生化/生理作用

Troponin T1 (TNNT1) plays a vital role in calcium regulation of striated muscle contraction and relaxation. Mutation in the gene is associated with the development of nemaline myopathy.

特点和优势

Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:
  • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
  • Protein array of 364 human recombinant protein fragments.

联系

Corresponding Antigen APREST87837

外形

Solution in phosphate buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide.

法律信息

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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Histone deacetylase inhibition elicits an evolutionarily conserved self-renewal program in embryonic stem cells.
Ware C B, et al.
Cell Stem Cell, 4(4), 359-369 (2009)
TNNT1, TNNT2, and TNNT3: Isoform Genes, Regulation, and Structure-Function Relationships.
Wei B and Jin J P
Gene, 582(1), 1-13 (2016)
Joshua S Clayton et al.
Acta neuropathologica communications, 8(1), 142-142 (2020-08-21)
Ovine congenital progressive muscular dystrophy (OCPMD) was first described in Merino sheep flocks in Queensland and Western Australia in the 1960s and 1970s. The most prominent feature of the disease is a distinctive gait with stiffness of the hind limbs
Alice Rannou et al.
Molecular therapy. Methods & clinical development, 18, 446-463 (2020-07-23)
Myocardial infarction is one of the leading causes of mortality and morbidity worldwide. Whereas transplantation of several cell types into the infarcted heart has produced promising preclinical results, clinical studies using analogous human cells have shown limited structural and functional
Cecilia Lindskog et al.
BMC genomics, 16, 475-475 (2015-06-26)
To understand cardiac and skeletal muscle function, it is important to define and explore their molecular constituents and also to identify similarities and differences in the gene expression in these two different striated muscle tissues. Here, we have investigated the

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