I7125
5-碘-2′-脱氧尿苷
≥99% (HPLC), synthetic (organic), powder or crystals
别名:
1-(2-脱氧-β-D-呋喃核糖基）-5-碘尿嘧啶, 2′-脱氧-5-碘尿苷, 5-HIAA, IDU, IdUrd, 碘苷
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关于此项目
经验公式（希尔记法）:
C9H11IN2O5
化学文摘社编号:
分子量:
354.10
Beilstein:
30397
EC 号:
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51
产品名称
5-碘-2′-脱氧尿苷, ≥99% (HPLC)
生物来源
synthetic (organic)
方案
≥99% (HPLC)
表单
powder or crystals
mp
194 °C (lit.)
溶解性
1 N NH4OH: 50 mg/mL, clear to very slightly hazy, colorless to light yellow
储存温度
2-8°C
SMILES字符串
OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(I)C(=O)NC2=O
InChI
1S/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
InChI key
XQFRJNBWHJMXHO-RRKCRQDMSA-N
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应用
5-碘-2′-脱氧尿苷已用于分子梳检测或DNA纤维检测。
5-碘-2′-脱氧尿苷（5-IUdR；IdUrd）是一种嘧啶类似物（卤代胸苷），具有抗牛痘病毒（正痘病毒）活性。 IdUrd在人类癌症研究中被用作放射增敏剂。
生化/生理作用
5-碘-2′-脱氧尿苷可防止体外DNA病毒复制，疱疹病毒和痘病毒中可见这一现象。它具有致畸、促肿瘤、致突变和免疫抑制性。5-碘-2′-脱氧尿苷可用于外用治疗，有效抵抗上皮感染。
警示用语：
Warning
危险分类
Eye Irrit. 2 - Muta. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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