M8407
甲氨蝶呤 水合物
powder, suitable for cell culture, BioReagent
别名:
对-[(2,4-二氨基喋啶-6)-N-甲基甲氨基]苯甲酰谷氨酸 水合物, L-氨甲喋呤 水合物, MTX 水合物, 氟安定 水合物, 氨甲叶酸 水合物, 氨甲喋呤 水合物
选择尺寸
关于此项目
产品名称
甲氨蝶呤 水合物, powder, BioReagent, suitable for cell culture, ≥98% (HPLC)
SMILES string
[H]O[H].CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O
InChI
1S/C20H22N8O5.H2O/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30;/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27);1H2/t13-;/m0./s1
InChI key
FPJYMUQSRFJSEW-ZOWNYOTGSA-N
product line
BioReagent
assay
≥98% (HPLC)
form
powder
technique(s)
cell culture | mammalian: suitable
solubility
H2O: insoluble
antibiotic activity spectrum
neoplastics
parasites
mode of action
enzyme | inhibits
storage temp.
−20°C
Quality Level
Gene Information
human ... DHFR(1719)
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Application
- 用于球状体形成分析培养物中的二氢叶酸(DHFR)抑制剂
- 用作杜氏改良Eagles培养基（DMEM）组分，筛选转染细胞
- 活力和共培养分析
Biochem/physiol Actions
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I make a solution of Methotrexate hydrate, Product M8407?
Methoxtrexate is soluble in 1M NaOH or NH4OH (10 mg/ml). For use in cell culture, sodium carbonate buffer (pH 9.0-9.5) can be used to dissolve methotrexate.
How do I store a stock solution of Methotrexate hydrate, Product M8407?
A sterile solution of methotrexate can be stored at 2-8 °C for approximately 30 days.
How do I sterilize a solution of Methotrexate hydrate, Product M8407?
A solution of methotrexate can be sterile filtered using a 0.22 mm filter
How often does Methotrexate hydrate, Product M8407, need to be added to the media during selection?
Fresh methotrexate should be added each time the culture media is changed. Regardless of cell growth, most media will need to be changed at least once a week.
How do I find price and availability?
There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 or view local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
My question is not addressed here, how can I contact Technical Service for assistance?
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