detection method
colorimetric, fluorometric
relevant disease(s)
cancer; neurological disorders
storage temp.
−20°C
General description
三磷酸腺苷(ATP)是一种仅在线粒体内形成的三磷酸核苷。这是一种高能分子,被称为所有生命系统的能量货币。包含在ATP的磷酸键中的化学能量驱动着大多数的细胞过程。诸如Leber遗传性视神经病变、Leigh综合征、神经病、共济失调以及色素性视网膜炎等遗传疾病都会影响线粒体内的ATP生成。
Application
ATP检测试剂盒已用于通过对样本中ATP的荧光检测而对ATP浓度进行量化。
适于测定不同样品中的ATP,如动物组织和细胞培养样品。
Biochem/physiol Actions
ATP比色/荧光检测试剂盒是一种用于测定各种样品中ATP的灵敏检测(比色检测为2-10 nmole/孔而荧光检测为20-1,000 pmole/孔)。ATP的浓度是通过磷酸化甘油而测定,可产生与存在的ATP量成比例的比色(570 nm)或荧光(lex = 535/lem = 587 nm)产物。
Other Notes
荧光检测比比色检测具有10-100倍更高的灵敏度。
Still not finding the right product?
Explore all of our products under ATP 检测试剂盒
仅试剂盒组分
产品编号
说明
- ATP Assay Buffer
- ATP Probe, in DMSO
- ATP Converter
- Developer Mix
- ATP Standard, 1.0 μmole
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
存储类别
10 - Combustible liquids
flash_point_f
188.6 °F
flash_point_c
87 °C
相关内容
Instructions
E Alirol et al.
Oncogene, 25(34), 4706-4716 (2006-08-08)
Mitochondria are key players in several cellular functions including growth, division, energy metabolism, and apoptosis. The mitochondrial network undergoes constant remodelling and these morphological changes are of direct relevance for the role of this organelle in cell physiology. Mitochondrial dysfunction
Melatonin Balance the Autophagy and Apoptosis by Regulating UCP2 in the LPS-Induced Cardiomyopathy.
Pan P, et al.
Molecules (Basel), 23(3), 675-675 (2018)
Enhanced mitochondrial fission suppresses signaling and metastasis in triple-negative breast cancer.
Brock A Humphries et al.
Breast cancer research : BCR, 22(1), 60-60 (2020-06-07)
Mitochondrial dynamics underlies malignant transformation, cancer progression, and response to treatment. Current research presents conflicting evidence for functions of mitochondrial fission and fusion in tumor progression. Here, we investigated how mitochondrial fission and fusion states regulate underlying processes of cancer
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MAK190-1KT | 04061834065760 |
