PLA0196
Rabbit anti-STUB1/CHIP Antibody, Affinity Purified
Powered by Bethyl Laboratories, Inc.
别名:
CHIP, CLL-associated antigen KW-8, E3 ubiquitin protein ligase, HSPABP2, NY-CO-7, SCAR16, SDCCAG7, STIP1 homology and U box-containing protein 1, STIP1 homology and U-box containing protein 1, UBOX1, antigen NY-CO-7, carboxy terminus of Hsp70-interacting protein, heat shock protein A binding protein 2 (c-terminal), serologically defined colon cancer antigen 7
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Species reactivity:
mouse, human
Technique(s):
immunoprecipitation (IP): 2-5 μg/mg, western blot: 1:2,000- 1:10,000
Application:
IP, WB
Citations:
-
biological source
rabbit
Quality Segment
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
species reactivity
mouse, human
technique(s)
immunoprecipitation (IP): 2-5 μg/mg, western blot: 1:2,000- 1:10,000
accession no.
NP_005852.2
shipped in
wet ice
storage temp.
2-8°C
Gene Information
rabbit ... STUB1/CHIP(10273)
Immunogen
The epitope recognized by PLA0196 maps to a region between residue 1 and 50 of human STIP1 homology and U-box containing protein 1 (carboxy terminus of Hsp70-interacting protein) using the numbering given in entry NP_005852.2 (GeneID 10273).
Physical form
Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide
Other Notes
STUB1/CHIP is an E3 ubiquitin ligase and co-chaperone of heat-shock protein 70 (Hsp70). STUB1/CHIP interacts with Hsp70 to monitor protein folding and direct misfolded proteins for proteasomal degradation. It has been found to also associate with Hsp90 to remove phosphorylated protein tau, a protein that accumulates in the brains of Alzheimer′s and Down′s syndrome patients. STUB1/CHIP has been reported to also have intrinsic chaperone activity and recognize non-native proteins in response to heat stress. In this way, STUB1/CHIP has been shown to be a direct chaperone for p53.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable