SAB3500152
Anti-NSA1 antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
别名:
Anti-NOP seven-associated protein 1, Anti-WD repeat-containing protein 74, Anti-WDR74
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), IF, IHC, WB
Citations:
4
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
rat, human, mouse
technique(s)
immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... WDR74(54663)
General description
WD repeat domain 74 (WDR74), also known as NOP seven-associated protein 1 (NSA1), is encoded by the gene mapped to human chromosome 11q12.3. The encoded protein is mainly localized in the nucleus and it contains six WD40 repeats.
Immunogen
NSA1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human NSA1.
Biochem/physiol Actions
WD repeat domain 74 (WDR74) along with the nucleolar AAA-ATPase NVL2, plays a vital role in an early cleavage of the pre-rRNA processing pathway. It is also implicated in various biological processes, including cell cycle control and apoptosis. In mouse, this protein plays an essential role in RNA transcription, processing and/or stability during preimplantation development.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied in PBS with 0.02% sodium azide.
Other Notes
The action of this antibody can be blocked using blocking peptide SBP3500152.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Genome-wide analysis of non-coding regulatory mutations in cancer
Weinhold N, et al.
Nature Genetics, 46(11), 1160-1160 (2014)
Wdr74 Is Required for Blastocyst Formation in the Mouse
Maserati M, et al.
PLoS ONE, 6(7), e22516-e22516 (2011)
Genes Involved in Human Ribosome Biogenesis are Transcriptionally Upregulated in Colorectal Cancer
Mansilla F, et al.
Scholarly Research Exchange (2009)
WDR74 participates in an early cleavage of the pre-rRNA processing pathway in cooperation with the nucleolar AAA-ATPase NVL2.
Hiraishi N, et al.
Biochemical and Biophysical Research Communications, 495(1), 116-123 (2018)
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