Skip to Content
Merck
CN

SAB3500152

Anti-NSA1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-NOP seven-associated protein 1, Anti-WD repeat-containing protein 74, Anti-WDR74

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), IF, IHC, WB
Citations:
4

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

rat, human, mouse

technique(s)

immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

NCBI accession no.

Q6RFH5

UniProt accession no.

Q6RFH5

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... WDR74(54663)

General description

WD repeat domain 74 (WDR74), also known as NOP seven-associated protein 1 (NSA1), is encoded by the gene mapped to human chromosome 11q12.3. The encoded protein is mainly localized in the nucleus and it contains six WD40 repeats.

Immunogen

NSA1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human NSA1.

Biochem/physiol Actions

WD repeat domain 74 (WDR74) along with the nucleolar AAA-ATPase NVL2, plays a vital role in an early cleavage of the pre-rRNA processing pathway. It is also implicated in various biological processes, including cell cycle control and apoptosis. In mouse, this protein plays an essential role in RNA transcription, processing and/or stability during preimplantation development.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in PBS with 0.02% sodium azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500152.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
56691001

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

WDR74 participates in an early cleavage of the pre-rRNA processing pathway in cooperation with the nucleolar AAA-ATPase NVL2.
Hiraishi N, et al.
Biochemical and Biophysical Research Communications, 495(1), 116-123 (2018)
Genes Involved in Human Ribosome Biogenesis are Transcriptionally Upregulated in Colorectal Cancer
Mansilla F, et al.
Scholarly Research Exchange (2009)
Genome-wide analysis of non-coding regulatory mutations in cancer
Weinhold N, et al.
Nature Genetics, 46(11), 1160-1160 (2014)
Wdr74 Is Required for Blastocyst Formation in the Mouse
Maserati M, et al.
PLoS ONE, 6(7), e22516-e22516 (2011)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service