SAB3500204
抗-CX3CR1 兔抗
affinity isolated antibody, buffered aqueous solution
别名:
抗-V28
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), FACS, IF, IHC, WB
Citations:
5
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
predicted mol wt 50 kDa
species reactivity
mouse, human, rat
technique(s)
flow cytometry: suitable, immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CX3CR1(1524)
General description
C-X3-C基序趋化因子受体1（CX3CR1）是七跨膜结构域G蛋白偶联受体。该基因位于人染色体3p22.2上。CX3CR1在不同类型的炎症细胞中表达。
Immunogen
产生针对对应于人CX3CR1氨基酸2至21的肽的CX3CR1抗体。该序列与小鼠和大鼠CX3CR1的序列不同，有四个氨基酸（3，4）。
Application
兔抗CX3CR1抗体可用于蛋白质印迹。
Biochem/physiol Actions
C-X3-C基序趋化因子受体1（CX3CR1）充当fractalkine的受体。它与炎症和血管疾病的进展有关。
Features and Benefits
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用，我们将全额退款或安排替代抗体。了解更多信息。
Physical form
以含有0.02%叠氮化钠的PBS形式提供。
Other Notes
可以使用阻断肽SBP3500204阻断该抗体的作用。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Polymorphisms in the microglial marker molecule CX3CR1 affect the blood volume of the human brain
Sakai M, et al.
Psychiatry and Clinical Neurosciences, 72(6), 409-422 (2018)
Chris Rudyk et al.
Journal of neuroinflammation, 16(1), 120-120 (2019-06-09)
Leucine-rich repeat kinase 2 (LRRK2) is a common gene implicated in Parkinson's disease (PD) and is also thought to be fundamentally involved in numerous immune functions. Thus, we assessed the role of LRRK2 in the context of the effects of
Leucine-rich repeat kinase-2 (LRRK2) modulates paraquat-induced inflammatory sickness and stress phenotype
Rudyk C, et al.
Journal of Neuroinflammation, 16(1), 120-120 (2019)
Glabridin Therapy Reduces Chronic Allodynia, Spinal Microgliosis, and Dendritic Spine Generation by Inhibiting Fractalkine-CX3CR1 Signaling in a Mouse Model of Tibial Fractures.
Long, et al.
Brain sciences, 13 (2023)
Merlin G Butler et al.
International journal of molecular sciences, 16(3), 6464-6495 (2015-03-25)
Recently, autism-related research has focused on the identification of various genes and disturbed pathways causing the genetically heterogeneous group of autism spectrum disorders (ASD). The list of autism-related genes has significantly increased due to better awareness with advances in genetic
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