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Merck
CN

SAB3500278

Anti-IRAK antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):

Anti-IL-1-Receptor Associated Kinase

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD01092386

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

predicted mol wt 78 kDa

species reactivity

mouse, human, rat

technique(s)

immunocytochemistry: suitable, immunofluorescence: suitable, immunoprecipitation (IP): suitable, indirect ELISA: suitable, western blot: suitable

NCBI accession no.

P51617

UniProt accession no.

P51617

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... IRAK1(3654)

Immunogen

IRAK antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human IRAK.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in PBS with 0.02% sodium azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500278.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
10070402

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Juhee Jeon et al.
Biochemical pharmacology, 89(4), 515-525 (2014-04-17)
The ligation of interleukin-1 receptor (IL-1R) or tumor necrosis factor receptor 1 (TNFR1) induces the recruitment of adaptor proteins and their concomitant ubiquitination to the proximal receptor signaling complex, respectively. Such are upstream signaling events of IKK that play essential
Robert B Lochhead et al.
PLoS pathogens, 10(6), e1004212-e1004212 (2014-06-27)
MicroRNAs have been shown to be important regulators of inflammatory and immune responses and are implicated in several immune disorders including systemic lupus erythematosus and rheumatoid arthritis, but their role in Lyme borreliosis remains unknown. We performed a microarray screen

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