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Merck
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SAB3500288

Anti-CUEDC1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-CUE Domain-Containing Protein 1

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), IF, IHC, WB
Citations:
1

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, mouse, rat

technique(s)

immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

NCBI accession no.

AAH56882

UniProt accession no.

Q9NWM3

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... CUEDC1(404093)

Immunogen

CUEDC1 antibody was raised against a 16 amino acid peptide near the carbocy terminus of human CUEDC1.

Biochem/physiol Actions

CUEDC1 (CUE domain containing 1) might be involved in protein trafficking and degradation. Changes in this gene are linked with early stage cervical cancer. It is highly methylated in the placental tissue of preeclampsia patients. CUEDC1 is suggested to control trophoblast invasion by participating in the TGF (transforming growth factor)-β/Smad (mothers against decapentaplegic homolog) signaling pathway. The gene is mapped to human chromosome 17q23.

Features and Benefits

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Physical form

Supplied in PBS with 0.02% sodium azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500288.

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
48290804

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Y-H Yan et al.
European review for medical and pharmacological sciences, 17(22), 3083-3094 (2013-12-05)
Preeclampsia is a complication of pregnancy that severely threatens the health of the mother and infant, yet the mechanism of pathogenesis remains unclear. In this article, gene array technology was applied to identify the genes related to the pathogenesis of

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