NK2 homeobox 1 (NKX2-1) is expressed in epithelial cells of the thyroid gland and lungs. The gene encoding NKX2-1 is localized on human chromosome 14q13.

Antibody was raised against a 16 amino acid peptide near the amino terminus of human NKX2-1.

NK2 homeobox 1(NKX2-1) has a role in the development of thyroid glands, lungs and brain. It modulates gene expression during embryogenesis. NKX2-1 has been found to be expressed in adenocarcinoma and small cell lung cancer. This protein acts as an immunohistological marker to distinguish between primary lung carcinoma and non-pulmonary cancer.

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The action of this antibody can be blocked using blocking peptide SBP3500757.

Supplied at 1 mg/mL in PBS with 0.02% sodium azide.

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