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Merck
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SAB3501081

Anti-AQP2 antibody produced in rabbit

affinity isolated antibody

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
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form

buffered aqueous solution

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

mol wt

predicted mol wt 30 kDa

species reactivity

human, rat, mouse

concentration

1 mg/mL

technique(s)

ELISA: suitable, immunoblotting: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... AQP2(359)

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Immunogen

Antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AQP2.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 1 mg/mL in PBS with 0.02% sodim azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3501081.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Inherited secondary nephrogenic diabetes insipidus: concentrating on humans
Bockenhauer D, et al
American Journal of Physiology: Renal Physiology, 304, F1037-F1042 (2013)
B M Denker et al.
The Journal of biological chemistry, 263(30), 15634-15642 (1988-10-25)
A novel Mr 28,000 integral membrane protein ("28kDa") was identified in human erythrocytes and found entirely associated with the Triton X-100 insoluble membrane skeletons. Antibodies to 28kDa reacted strongly on immunoblots with 28kDa and a diffuse region of Mr 35,000-60,000
Maria Barile et al.
Molecular & cellular proteomics : MCP, 4(8), 1095-1106 (2005-05-21)
Vasopressin acts on renal collecting duct cells to stimulate translocation of aquaporin-2 (AQP2)-containing membrane vesicles from throughout the cytoplasm to the apical region. The vesicles fuse with the plasma membrane to increase water permeability. To identify the intracellular membrane compartments
Annette Hus-Citharel et al.
Endocrinology, 155(11), 4483-4493 (2014-08-27)
Apelin receptors (ApelinRs) are expressed along an increasing cortico-medullary gradient in collecting ducts (CDs). We showed here that iv injection of apelin 17 (K17F) in lactating rats characterized by increases in both synthesis and release of arginine vasopressin (AVP) increased

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