SML2220
SGC-AAK1-1N
≥98% (HPLC)
别名:
N-(6-(3-(Cyclopropanesulfonamido)phenyl)-1H-indazol-3-yl)isobutyramide, SGC-AAK1-1 Negative Control
产品名称
SGC-AAK1-1N, ≥98% (HPLC)
InChI
1S/C20H22N4O3S/c1-12(2)20(25)21-19-17-9-6-14(11-18(17)22-23-19)13-4-3-5-15(10-13)24-28(26,27)16-7-8-16/h3-6,9-12,16,24H,7-8H2,1-2H3,(H2,21,22,23,25)
InChI key
RAIAORGFMNXPOV-UHFFFAOYSA-N
SMILES string
O=C(C(C)C)NC1=NNC2=C1C=CC(C3=CC(NS(C4CC4)(=O)=O)=CC=C3)=C2
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
Negative control analog for the AAK1 and BIKE/BMP2K inhibitor SGC-AAK1-1.
SGC-AAK1-1N is a structure analog of and the recommended negative control for SGC-AAK1-1 (AAK1 IC50 = 11 μM and 270 nM, respectively, by coupled enzyme assay; KD = 8.8 μM/AAK1 & >10 μM/BIKE with SGC-AAK1-1N vs. KD = 26 nM/AAK1 & 930 nM/BIKE with SGC-AAK1-1). For characterization details of the active probe, SGC-AAK1-1, please visit the SGC-AAK1-1 probe summary on the Structural Genomics Consortium (SGC) website.
SGC-AAK1-1, the active probe, is available from Sigma. To learn more about and purchase SGC-AAK1-1, click here.
To learn about other SGC chemical probes, visit sigma.com/sgc
SGC-AAK1-1, the active probe, is available from Sigma. To learn more about and purchase SGC-AAK1-1, click here.
To learn about other SGC chemical probes, visit sigma.com/sgc
Features and Benefits
SGC-AAK1-1N is a negative control for SGC-AAK1-1, a chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC chemical probes, visit sigma.com/SGC
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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