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756822

氧化氘

Name: 氧化氘
Brand: ALDRICH

filtered, 99.8 atom % D

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别名:

氘化水, 氘代水, 重水

经验公式（希尔记法）:

D₂O

CAS号:

7789-20-0

分子量:

20.03

EC 号:

232-148-9

MDL编号:

MFCD00044636

PubChem化学物质编号:

329766620

NACRES:

NA.12

同位素纯度

99.8 atom % D

形式

liquid

technique(s)

HPLC: suitable
bio NMR: suitable
protein expression: suitable

bp

101.4 °C (lit.)

mp

3.8 °C (lit.)

密度

1.107 g/mL at 25 °C

SMILES string

[2H]O[2H]

InChI

1S/H2O/h1H2/i/hD2

InChI key

XLYOFNOQVPJJNP-ZSJDYOACSA-N

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一般描述

氧化氘（D₂O）也称为重水。它是水的氘化形式, H₂O 中的两个质子被氘同位素所取代。

应用

D₂O 可用作以下应用中的溶剂：

高分辨率NMR（核磁共振）
FTIR （傅里叶变换红外）
生物核磁共振研究
极化可见光拉曼光谱研究
蛋白质表达

D₂O 可通过H-D交换反应制备氘标记化合物，用于制药、生物分析、生物、环境化学等领域，可使用合适的分析方法研究药物代谢机制、反应机制、生物分子结构、食品残留农药等。.

包装

该产品可以大包装形式供货，也可按需进行包装。如需关于价格、供货形式及包装的信息，请联系稳定同位素客户服务。

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

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示例

T1503

货号

25G

包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

输入内容 1.000309185)

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Dihedral angles of trialanine in D2O determined by combining FTIR and polarized visible Raman spectroscopy.

R Schweitzer-Stenner et al.

Journal of the American Chemical Society, 123(39), 9628-9633 (2001-09-27)

We have measured the polarized visible Raman and FTIR spectra of trialanine and triglycine in D(2)O at acid, neutral, and alkaline pD. From the Raman spectra we obtained the isotropic and the anisotropic scattering. A self-consistent spectral analysis of the

The Structural Basis for Low Conductance in the Membrane Protein VDAC upon β-NADH Binding and Voltage Gating.

Raphael Böhm et al.

Structure (London, England : 1993), 28(2), 206-214 (2019-12-22)

The voltage-dependent anion channel (VDAC) forms the primary diffusion pore of the outer mitochondrial membrane. In its apo form, VDAC adopts an open conformation with high conductance. States of lower conductance can be induced by ligand binding or the application

Moderate hyperventilation during intravenous anesthesia increases net cerebral lactate efflux.

Frank Grüne et al.

Anesthesiology, 120(2), 335-342 (2013-09-07)

Hyperventilation is known to decrease cerebral blood flow (CBF) and to impair cerebral metabolism, but the threshold in patients undergoing intravenous anesthesia is unknown. The authors hypothesized that reduced CBF associated with moderate hyperventilation might impair cerebral aerobic metabolism in

Determination of steady-state protein breakdown rate in vivo by the disappearance of protein-bound tracer-labeled amino acids: a method applicable in humans.

Lars Holm et al.

American journal of physiology. Endocrinology and metabolism, 304(8), E895-E907 (2013-02-21)

A method to determine the rate of protein breakdown in individual proteins was developed and tested in rats and confirmed in humans, using administration of deuterium oxide and incorporation of the deuterium into alanine that was subsequently incorporated into body

Assessment of cardiac proteome dynamics with heavy water: slower protein synthesis rates in interfibrillar than subsarcolemmal mitochondria.

Takhar Kasumov et al.

American journal of physiology. Heart and circulatory physiology, 304(9), H1201-H1214 (2013-03-05)

Traditional proteomics provides static assessment of protein content, but not synthetic rates. Recently, proteome dynamics with heavy water ((2)H2O) was introduced, where (2)H labels amino acids that are incorporated into proteins, and the synthesis rate of individual proteins is calculated

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氧化氘