AOC2
amine oxidase, copper containing 2 (retina-specific)
Synonyms:
DAO2, RAO
Species:
Human AOC2 (314), Mouse Aoc2 (237940), Domestic Rabbit AOC2 (100353051), domestic cat AOC2 (101080592), dog AOC2 (490957), sheep AOC2 (101106783), Thale Cress AOC2 (822168), cow AOC2 (100336082)
UniProtKB ID:
Gene ID:
- Human(314) Summary: Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
- Mouse(237940) amine oxidase, copper containing 2 (retina-specific)
- Domestic Rabbit(100353051) amine oxidase, copper containing 2 (retina-specific)
- domestic cat(101080592) amine oxidase, copper containing 2 (retina-specific)
- dog(490957) amine oxidase, copper containing 2 (retina-specific)
- sheep(101106783) amine oxidase, copper containing 2 (retina-specific)
- Thale Cress(822168) allene oxide cyclase 2
- cow(100336082) amine oxidase, copper containing 2 (retina-specific)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-AOC2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, mouse, rabbit
Application
western blot