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Merck
CN

AV45055

Sigma-Aldrich

Anti-AOC2 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-Amine oxidase, copper containing 2 (retina-specific), Anti-DAO2, Anti-RAO

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

84 kDa

species reactivity

dog, bovine, mouse, human, rabbit, horse

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NP_001149

UniProt accession no.

O75106

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... AOC2(314)

Immunogen

Synthetic peptide directed towards the middle region of human AOC2

Application

Anti-AOC2 antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml.

Biochem/physiol Actions

Amine oxidase, copper containing 2 (retina-specific) belongs to the copper amine oxidases family that converts amines to aldehydes and ammonia in the presence of copper and quinone as cofactors. AOC2 degrades dopamine, histamine and putrescine and modulates the signal transmission in the retina. The AOC2 gene mutations may cause hereditary ocular diseases.

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Other Notes

Synthetic peptide located within the following region: QATMVDIHILVGKGAVQLLPGAVCVFEEAQGLPLRRHHNYLQNHFYGGLA

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
QC15034

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Sam Kaitaniemi et al.
Cellular and molecular life sciences : CMLS, 66(16), 2743-2757 (2009-07-10)
Semicarbazide-sensitive amine oxidases (SSAOs) catalyze oxidative deamination of primary amines, but the true physiological function of these enzymes is still poorly understood. Here, we have studied the functional and structural characteristics of a human cell-surface SSAO, AOC2, which is homologous
Qiang Zhang et al.
Gene, 318, 45-53 (2003-10-31)
We have previously cloned a human, retina-specific, amine oxidase gene (RAO, gene symbol: AOC2), a member of the copper-binding amine oxidase super family. AOC2 shares sequence identity with the human kidney amine oxidase gene (KAO, gene symbol: AOC1) and the

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