APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
Synonyms:
FE65, MGC:9072, RIR
Species:
Human APBB1 (322), Mouse Apbb1 (11785), Rat Apbb1 (29722), naked mole-rat Apbb1 (101699658), domestic cat APBB1 (101090045), domestic guinea pig Apbb1 (100735070), cow APBB1 (505096), Domestic Rabbit APBB1 (100354159), dog APBB1 (476833), chicken APBB1 (100859045) ...More
UniProtKB ID:
Gene ID:
- Human(322) Summary: The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]
- Mouse(11785) amyloid beta (A4) precursor protein-binding, family B, member 1
- Rat(29722) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
- naked mole-rat(101699658) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
- domestic cat(101090045) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
- domestic guinea pig(100735070) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
- cow(505096) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
- Domestic Rabbit(100354159) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
- dog(476833) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
- chicken(100859045) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
- Horse(100069964) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
- Zebrafish(565164) amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-APBB1/FE65 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-APBB1 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-Phospho-APBB1-S347 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
KD-Validated Anti APBB1 Antibody, clone 23GB3665, Rabbit Monoclonal, clone 23GB3665, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human
Application
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Anti-APBB1 (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot