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SAB6012305

KD-Validated Anti APBB1 Antibody, clone 23GB3665, Rabbit Monoclonal

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clone 23GB3665, recombinant rabbit monoclonal, expressed in HEK293 cells

Synonym(s):

FE65, Fe65, RIR

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About This Item

UNSPSC Code:
12352203

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Product Name

KD-Validated Anti APBB1 Antibody, clone 23GB3665, Rabbit Monoclonal, clone 23GB3665, recombinant rabbit monoclonal, expressed in HEK293 cells

biological source

rabbit (Monoclonal)

recombinant

expressed in HEK 293 cells

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

23GB3665, recombinant monoclonal

form

buffered aqueous glycerol solution

mol wt

77 kDa

species reactivity

human

packaging

vial of 1.5 mL

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation

Quality Level

100

Gene Information

human ... APBB1(322)

sustainability

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concentration

0.31 mg/ml

technique(s)

flow cytometry: 1:2000
immunofluorescence: 1:100-:1000
western blot: 1:1,000-1:5,000

isotype

IgG

Ensembl | human accession no.

ENSG00000166313

NCBI accession no.

NP_001155.1

UniProt accession no.

O00213

greener alternative category

DfS-Developed

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

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General description

The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer′s disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product′s nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer′s disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]
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Immunogen

A synthesized peptide corresponding to a sequence within amino acids 650-710 of human FE65 [NP_001155.1].

Other Notes

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.

Physical form

Solution in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.

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