Merck
CN

CXCL1

chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)

Synonyms:
FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1
Species:
UniProtKB ID:
Gene ID:
  • Human(2919) Summary: This gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signal through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Jan 2012]
  • Mouse(14825) chemokine (C-X-C motif) ligand 1
  • Rat(81503) chemokine (C-X-C motif) ligand 1
  • domestic guinea pig(100135510) chemokine (C-X-C motif) ligand 1
  • Horse(100034121) chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
  • naked mole-rat(101705558) chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
  • sheep(443380) chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)

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ELISA

Product Number
Description
Species
Rat CINC-1 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
rat
Human GRO-α / CXCL1 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Mouse KC / CXCL1 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CXCL1 antibody produced in mouse, clone 2D7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-CXCL1, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-CXCL1/GROa Antibody, clone HL2401, ,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)

inhibition assay

western blot

Proteins

Product Number
Description
Species
GROα human, ≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture,
Species
human
GRO/KC (CXCL1) from rat, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
rat
KC (CXCL1) from mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
mouse
GRO/KC from mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Species
mouse

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Cxcl1,
Species
mouse
MISSION® esiRNA, targeting human CXCL1,
Species
human