Merck
CN

CYP19A1

cytochrome P450, family 19, subfamily A, polypeptide 1

Synonyms:
ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM
Species:
Human CYP19A1 (1588), Mouse Cyp19a1 (13075), Rat Cyp19a1 (25147), Goat CYP19A1 (100861413), Horse CYP19A1 (100009712), dog CYP19A1 (494003), chicken CYP19A1 (414854), Domestic Rabbit CYP19A1 (100328545), cow CYP19A1 (281740)
UniProtKB ID:
P11511, Q16731, Q3B764, Q58FA0
Gene ID:
  • Human(1588) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq, Jul 2008]
  • Mouse(13075) cytochrome P450, family 19, subfamily a, polypeptide 1
  • Rat(25147) cytochrome P450, family 19, subfamily a, polypeptide 1
  • Goat(100861413) cytochrome P450, family 19, subfamily A, polypeptide 1
  • Horse(100009712) cytochrome P450, family 19, subfamily A, polypeptide 1
  • dog(494003) cytochrome P450, family 17, subfamily A, polypeptide 1
  • chicken(414854) cytochrome P450, family 19, subfamily A, polypeptide 1
  • Domestic Rabbit(100328545) cytochrome P450, family 19, subfamily A, polypeptide 1
  • cow(281740) cytochrome P450, family 19, subfamily A, polypeptide 1

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB4500606
Anti-Cytochrome P450 19A1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
ABN30
Anti-Aromatase Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, canine, chimpanzee, human, pig, porcine, rhesus macaque
Application
western blot
SAB5702040
Anti-Aromatase (CYP19A1) Antibody, clone 5C5N7, Rabbit Monoclonal, ,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
HPA051194
Anti-CYP19A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
SAB1410280
Anti-CYP19A1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot

Cell Lines

Product Number
Description
Species
MTOXCE19A1
CypExpress™ Aromatase, ,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
BP1234
Letrozole, British Pharmacopoeia (BP) Reference Standard,
Species
human
L6545
Letrozole, ≥98% (HPLC),
Species
human
PHR1540
Letrozole, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
545872
(R)-(+)-Aminoglutethimide, 97%,
Species
human
D2016
Biochanin A, ,
Species
human, mouse

esiRNA

Product Number
Description
Species
EMU044241
MISSION® esiRNA, targeting mouse Cyp19a1,
Species
mouse
EHU036781
MISSION® esiRNA, targeting human CYP19A1,
Species
human