Merck
CN

GHRL

ghrelin/obestatin prepropeptide

Synonyms:
MTLRP
Species:
UniProtKB ID:
Gene ID:
  • Human(51738) Summary: This gene encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release. Obestatin was initially reported to be an endogenous ligand for the orphan G protein-coupled receptor GPR39 and was involved in satiety and decreased food intake; however, these findings are controversial. Recent reports show that obestatin is involved in inhibiting thirst and anxiety, improving memory, regulating sleep, affecting cell proliferation, and increasing the secretion of pancreatic juice enzymes. Alternative promoters and alternative splicing result in multiple transcript variants, some of which encode different protein isoforms and some of which do not encode a protein but may regulate the ghrelin-obestatin preproprotein expression. In addition, antisense transcripts for this gene have been identified and may also function in regulation of the ghrelin-obestatin preproprotein expression. [provided by RefSeq, Oct 2008]
  • Mouse(58991) ghrelin
  • Rat(59301) ghrelin/obestatin prepropeptide
  • Zebrafish(798613) ghrelin/obestatin preprohormone
  • chicken(408185) ghrelin/obestatin prepropeptide
  • naked mole-rat(101710248) ghrelin/obestatin prepropeptide
  • Horse(100058008) ghrelin/obestatin prepropeptide
  • domestic guinea pig(100717245) ghrelin/obestatin prepropeptide
  • sheep(442996) ghrelin/obestatin prepropeptide
  • Goat(100861189) ghrelin/obestatin prepropeptide
  • dog(403587) ghrelin/obestatin prepropeptide
  • domestic cat(493844) ghrelin/obestatin prepropeptide
  • cow(281192) ghrelin/obestatin prepropeptide

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ELISA

Product Number
Description
Species
Obestatin EIA Kit, for serum, plasma, culture supernatant and cell lysates,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-GHRL antibody produced in mouse, clone 4B8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-GHRL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-GHRL (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
Monoclonal Anti-GHRL antibody produced in mouse, clone 1C8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Monoclonal Anti-GHRL antibody produced in mouse, clone 3G3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA

Small Molecule - Inhibitor

Product Number
Description
Species
Obestatin human, ,
Species
human