CN
GRIA4
glutamate receptor, ionotropic, AMPA 4
Synonyms:
GLUR4, GLUR4C, GLURD, GluA4
Species:
Human GRIA4 (2893), Mouse Gria4 (14802), Rat Gria4 (29629), sheep GRIA4 (443274), domestic cat GRIA4 (101087003), chicken GRIA4 (396137), domestic guinea pig Gria4 (100728256), cow GRIA4 (529904), Horse GRIA4 (100061561), dog GRIA4 (489427)
UniProtKB ID:
Gene ID:
- Human(2893) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008]
- Mouse(14802) glutamate receptor, ionotropic, AMPA4 (alpha 4)
- Rat(29629) glutamate receptor, ionotropic, AMPA 4
- sheep(443274) glutamate receptor, ionotropic, AMPA 4
- domestic cat(101087003) glutamate receptor, ionotropic, AMPA 4
- chicken(396137) glutamate receptor, ionotropic, AMPA 4
- domestic guinea pig(100728256) glutamate receptor, ionotropic, AMPA 4
- cow(529904) glutamate receptor, ionotrophic, AMPA 4
- Horse(100061561) glutamate receptor, ionotropic, AMPA 4
- dog(489427) glutamate receptor, ionotropic, AMPA 4
- naked mole-rat(101698538) glutamate receptor, ionotropic, AMPA 4
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Small Molecule - Agonist
Product Number
Description
Species
2,6-Difluoro-4-[2-(phenylsulfonylamino)ethylthio]phenoxyacetamide, ≥98% (HPLC), solid,
Species
human
Small Molecule - Allosteric Modulator
Product Number
Description
Species
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-GRIA4 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
bovine, human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-GluR4/GluA4/GRIA4 Antibody, clone 4M5D0, Rabbit Monoclonal, ,
Species Reactivity
mouse, rat
Application
western blot
Anti-phospho GluR4 (Ser842) Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-Glutamate Receptor 4 Antibody, Chemicon®, from rabbit,
Species Reactivity
mouse, rat
Application
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-GLUR4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
western blot
Small Molecule - Blocker
Product Number
Description
Species
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Small Molecule - Mixed Agonist/Antagonist
Product Number
Description
Species